Fluticasone and salmeterol inhalation (Advair Diskus) is a steroid and bronchodilator combination medicine that is used to prevent asthma attacks. It is also used to prevent flare-ups or worsening of chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis and/or emphysema. In people with COPD, fluticasone and salmeterol (Advair Diskus) is for long-term treatment. In people with asthma, fluticasone and salmeterol (Advair Diskus) is for short-term treatment until symptoms are well controlled with with other medicines. Fluticasone and salmeterol inhalation (Advair Diskus) is for use in adults and children who are at least 4 years old. Advair HFA and AirDuo Respiclick are for use in adults and children who are at least 12 years old. Fluticasone and salmeterol (Advair Diskus) may also be used for purposes not listed in this medication guide.